SUMOylation mediates CtIP’s functions in DNA end resection and replication fork protection

Double-strand breaks and stalled replication forks are a significant threat to genomic stability that can lead to chromosomal rearrangements or cell death. The protein CtIP promotes DNA end resection, an early step in homologous recombination repair, and has been found to protect perturbed forks fro...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Locke, Andrew J, Hossain, Lazina, McCrostie, Glynnis, Ronato, Daryl A, Fitieh, Amira, Rafique, Tanzeem Ahmed, Mashayekhi, Fatemeh, Motamedi, Mobina, Masson, Jean-Yves, Ismail, Ismail Hassan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826263/
https://ncbi.nlm.nih.gov/pubmed/33406258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1232
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