SUMOylation mediates CtIP’s functions in DNA end resection and replication fork protection

Double-strand breaks and stalled replication forks are a significant threat to genomic stability that can lead to chromosomal rearrangements or cell death. The protein CtIP promotes DNA end resection, an early step in homologous recombination repair, and has been found to protect perturbed forks fro...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Locke, Andrew J, Hossain, Lazina, McCrostie, Glynnis, Ronato, Daryl A, Fitieh, Amira, Rafique, Tanzeem Ahmed, Mashayekhi, Fatemeh, Motamedi, Mobina, Masson, Jean-Yves, Ismail, Ismail Hassan
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Genome Integrity, Repair and Replication
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826263/
https://ncbi.nlm.nih.gov/pubmed/33406258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1232
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