SUMOylation mediates CtIP’s functions in DNA end resection and replication fork protection

Double-strand breaks and stalled replication forks are a significant threat to genomic stability that can lead to chromosomal rearrangements or cell death. The protein CtIP promotes DNA end resection, an early step in homologous recombination repair, and has been found to protect perturbed forks fro...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Locke, Andrew J, Hossain, Lazina, McCrostie, Glynnis, Ronato, Daryl A, Fitieh, Amira, Rafique, Tanzeem Ahmed, Mashayekhi, Fatemeh, Motamedi, Mobina, Masson, Jean-Yves, Ismail, Ismail Hassan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
Onderwerpen:
Genome Integrity, Repair and Replication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826263/
https://ncbi.nlm.nih.gov/pubmed/33406258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1232
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