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CtIP mediates replication fork recovery in a FANCD2-regulated manner

Fanconi anemia (FA) is a chromosome instability syndrome characterized by increased cancer predisposition. Within the FA pathway, an upstream FA core complex mediates monoubiquitination and recruitment of the central FANCD2 protein to sites of stalled replication forks. Once recruited, FANCD2 fulfil...

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Hlavní autoři: Yeo, Jung Eun, Lee, Eu Han, Hendrickson, Eric A., Sobeck, Alexandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065146/
https://ncbi.nlm.nih.gov/pubmed/24556218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu078
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