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Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase
Fanconi anemia (FA) pathway members, FANCD2 and FANCI, contribute to the repair of replication-stalling DNA lesions. FA pathway activation relies on phosphorylation of FANCI by the ataxia telangiectasia and Rad3-related (ATR) kinase, followed by monoubiquitination of FANCD2 and FANCI by the FA core...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458572/ https://ncbi.nlm.nih.gov/pubmed/22753026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks638 |
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