The Fanconi Anemia Protein FANCM Is Controlled by FANCD2 and the ATR/ATM Pathways

Genomic stability requires a functional Fanconi anemia (FA) pathway composed of an upstream “core complex” (FA proteins A/B/C/E/F/G/L/M) that mediates monoubiquitination of the downstream targets FANCD2 and FANCI. Unique among FA core complex members, FANCM has processing activities toward replicati...

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Main Authors: Sobeck, Alexandra, Stone, Stacie, Landais, Igor, de Graaf, Bendert, Hoatlin, Maureen E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757957/
https://ncbi.nlm.nih.gov/pubmed/19633289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007690
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