Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart

Mammalian RAD51 paralogs are implicated in the repair of collapsed replication forks by homologous recombination. However, their physiological roles in replication fork maintenance prior to fork collapse remain obscure. Here, we report on the role of RAD51 paralogs in short-term replicative stress d...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Somyajit, Kumar, Saxena, Sneha, Babu, Sharath, Mishra, Anup, Nagaraju, Ganesh
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787763/
https://ncbi.nlm.nih.gov/pubmed/26354865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv880
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