Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart

Mammalian RAD51 paralogs are implicated in the repair of collapsed replication forks by homologous recombination. However, their physiological roles in replication fork maintenance prior to fork collapse remain obscure. Here, we report on the role of RAD51 paralogs in short-term replicative stress d...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Somyajit, Kumar, Saxena, Sneha, Babu, Sharath, Mishra, Anup, Nagaraju, Ganesh
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787763/
https://ncbi.nlm.nih.gov/pubmed/26354865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv880
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