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Repeat instability during DNA repair: Insights from model systems

The expansion of repeated sequences is the cause of over 30 inherited genetic diseases, including Huntington disease, myotonic dystrophy (types 1 and 2), fragile X syndrome, many spinocerebellar ataxias, and some cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Repeat...

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Detalhes bibliográficos
Publicado no:Crit Rev Biochem Mol Biol
Main Authors: Usdin, Karen, House, Nealia C. M., Freudenreich, Catherine H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454471/
https://ncbi.nlm.nih.gov/pubmed/25608779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2014.999192
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