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DNA mismatch repair in trinucleotide repeat instability

Trinucleotide repeat expansions cause over 30 severe neuromuscular and neurodegenerative disorders, including Huntington’s disease, myotonic dystrophy type 1, and fragile X syndrome. Although previous studies have substantially advanced the understanding of the disease biology, many key features rem...

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Foilsithe in:Sci China Life Sci
Main Authors: Guo, Jinzhen, Chen, Luping, Li, Guo-Min
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430147/
https://ncbi.nlm.nih.gov/pubmed/29075942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11427-017-9186-7
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