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Trinucleotide repeat instability via DNA base excision repair

Trinucleotide repeat (TNR) instability is the cause of over 40 human neurodegenerative diseases and certain types of cancer. TNR instability can result from DNA replication, repair, recombination, and gene transcription. Emerging evidence indicates that DNA base damage and base excision repair (BER)...

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Bibliographic Details
Published in:DNA Repair (Amst)
Main Authors: Lai, Yanhao, Beaver, Jill M., Laverde, Eduardo, Liu, Yuan
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586489/
https://ncbi.nlm.nih.gov/pubmed/33087278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102912
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