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Instability of CTG Repeats is Governed by the Position of a DNA Base Lesion through Base Excision Repair
Trinucleotide repeat (TNR) expansions and deletions are associated with human neurodegeneration and cancer. However, their underlying mechanisms remain to be elucidated. Recent studies have demonstrated that CAG repeat expansions can be initiated by oxidative DNA base damage and fulfilled by base ex...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Public Library of Science
2013
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582642/ https://ncbi.nlm.nih.gov/pubmed/23468897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056960 |
| ট্যাগগুলো: |
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