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The Repeat Expansion Diseases: the dark side of DNA repair?

DNA repair normally protects the genome against mutations that threaten genome integrity and thus cell viability. However, growing evidence suggests that in the case of the Repeat Expansion Diseases, disorders that result from an increase in the size of a disease-specific microsatellite, the disease...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:DNA Repair (Amst)
Hauptverfasser: Zhao, Xiao-Nan, Usdin, Karen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522390/
https://ncbi.nlm.nih.gov/pubmed/26002199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.019
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