The biological effects of simple tandem repeats: Lessons from the repeat expansion diseases

Por Usdin, Karen
Publicado em 2008

Human nucleotide expansion disorders

Por Fry, Michael., Usdin, Karen.
Publicado em 2006

The GAA•TTC triplet repeat expanded in Friedreich’s ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner

Por Grabczyk, Ed, Usdin, Karen
Publicado em 2000

Alleviating transcript insufficiency caused by Friedreich’s ataxia triplet repeats

Por Grabczyk, Ed, Usdin, Karen
Publicado em 2000

NF-Y, AP2, Nrf1 and Sp1 regulate the fragile X-related gene 2 (FXR2)

Por Mahishi, Lata, Usdin, Karen
Publicado em 2006

ATR protects the genome against CGG·CCG-repeat expansion in Fragile X premutation mice

Por Entezam, Ali, Usdin, Karen
Publicado em 2008

Chromatin Remodeling in the Noncoding Repeat Expansion Diseases

Por Kumari, Daman, Usdin, Karen
Publicado em 2009

ATM and ATR protect the genome against two different types of tandem repeat instability in Fragile X premutation mice

Por Entezam, Ali, Usdin, Karen
Publicado em 2009

The distribution of repressive histone modifications on silenced FMR1 alleles provides clues to the mechanism of gene silencing in fragile X syndrome

Por Kumari, Daman, Usdin, Karen
Publicado em 2010

Is Friedreich ataxia an epigenetic disorder?

Por Kumari, Daman, Usdin, Karen
Publicado em 2012

Polycomb group complexes are recruited to reactivated FMR1 alleles in Fragile X syndrome in response to FMR1 transcription

Por Kumari, Daman, Usdin, Karen
Publicado no Hum Mol Genet (2014)

Repeat-mediated epigenetic dysregulation of the FMR1 gene in the fragile X-related disorders

Por Usdin, Karen, Kumari, Daman
Publicado no Front Genet (2015)

Sustained expression of FMR1 mRNA from reactivated fragile X syndrome alleles after treatment with small molecules that prevent trimethylation of H3K27

Por Kumari, Daman, Usdin, Karen
Publicado no Hum Mol Genet (2016)

Gender and cell-type specific effects of the transcription coupled repair protein, ERCC6/CSB, on repeat expansion in a mouse model of the Fragile X-related disorders

Por Zhao, Xiao-Nan, Usdin, Karen
Publicado em 2014

The transcription coupled repair protein ERCC6/CSB also protects against repeat expansion in a mouse model of the Fragile X premutation

Por Zhao, Xiao-Nan, Usdin, Karen
Publicado no Hum Mutat (2015)

The Repeat Expansion Diseases: the dark side of DNA repair?

Por Zhao, Xiao-Nan, Usdin, Karen
Publicado no DNA Repair (Amst) (2015)

Ups and Downs: Mechanisms of Repeat Instability in the Fragile X-Related Disorders

Por Zhao, Xiao-Nan, Usdin, Karen
Publicado no Genes (Basel) (2016)

The fragile X syndrome repeats form RNA hairpins that do not activate the interferon-inducible protein kinase, PKR, but are cut by Dicer

Por Handa, Vaishali, Saha, Tapas, Usdin, Karen
Publicado em 2003

SIRT1 Inhibition Alleviates Gene Silencing in Fragile X Mental Retardation Syndrome

Por Biacsi, Rea, Kumari, Daman, Usdin, Karen
Publicado em 2008

Repeat Expansion Affects Both Transcription Initiation and Elongation in Friedreich Ataxia Cells

Por Kumari, Daman, Biacsi, Rea Erika, Usdin, Karen
Publicado em 2011