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The fragile X syndrome repeats form RNA hairpins that do not activate the interferon-inducible protein kinase, PKR, but are cut by Dicer
We show here that under physiologically reasonable conditions, CGG repeats in RNA readily form hairpins. In contrast to its DNA counterpart that forms a complex mixture of hairpins and tetraplexes, r(CGG)(22) forms a single stable hairpin with no evidence for any other folded structure even at low p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275460/ https://ncbi.nlm.nih.gov/pubmed/14576312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg818 |
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