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ATR protects the genome against CGG·CCG-repeat expansion in Fragile X premutation mice
Fragile X mental retardation syndrome is a repeat expansion disease caused by expansion of a CGG·CCG-repeat tract in the 5′ UTR of the FMR1 gene. In humans, small expansions occur more frequently on paternal transmission while large expansions are exclusively maternal in origin. It has been suggeste...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2241920/ https://ncbi.nlm.nih.gov/pubmed/18160412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1136 |
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