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Gender and cell-type specific effects of the transcription coupled repair protein, ERCC6/CSB, on repeat expansion in a mouse model of the Fragile X-related disorders

The Repeat Expansion Diseases (REDs) are human genetic disorders that arise from expansion of a tandem repeat tract. The Fragile X-related disorders are members of this disease group in which the repeat unit is CGG/CCG and is located in the 5′ untranslated region of the FMR1 gene. Affected individua...

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Detalhes bibliográficos
Main Authors: Zhao, Xiao-Nan, Usdin, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067466/
https://ncbi.nlm.nih.gov/pubmed/24352881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22495
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