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Role of recombination and replication fork restart in repeat instability

Eukaryotic genomes contain many repetitive DNA sequences that exhibit size instability. Some repeat elements have the added complication of being able to form secondary structures, such as hairpin loops, slipped DNA, triplex DNA or G-quadruplexes. Especially when repeat sequences are long, these DNA...

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Bibliografiske detaljer
Udgivet i:DNA Repair (Amst)
Main Authors: Polleys, Erica J., House, Nealia C.M., Freudenreich, Catherine H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541998/
https://ncbi.nlm.nih.gov/pubmed/28641941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.018
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