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FLI1 level during megakaryopoiesis affects thrombopoiesis and platelet biology
Friend leukemia virus integration 1 (FLI1), a critical transcription factor (TF) during megakaryocyte differentiation, is among genes hemizygously deleted in Jacobsen syndrome, resulting in a macrothrombocytopenia termed Paris-Trousseau syndrome (PTSx). Recently, heterozygote human FLI1 mutations ha...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5492092/ https://ncbi.nlm.nih.gov/pubmed/28432223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-02-770958 |
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