ロード中...
Combinatorial Optimization of PEG Architecture and Hydrophobic Content Improves siRNA Polyplex Stability, Pharmacokinetics, and Potency In Vivo
A rationally-designed library of ternary siRNA polyplexes was developed and screened for gene silencing efficacy in vitro and in vivo with the goal of overcoming both cell-level and systemic delivery barriers. [2-(dimethylamino)ethyl methacrylate] (DMAEMA) was homopolymerized or colpolymerized (50 m...
保存先:
| 出版年: | J Control Release |
|---|---|
| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484420/ https://ncbi.nlm.nih.gov/pubmed/28366646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.03.389 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|