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Human papillomavirus regulates HER3 expression in head and neck cancer: implications for targeted HER3 therapy in HPV(+) patients

PURPOSE: Human papillomavirus (HPV) 16 plays an etiologic role in a growing subset of HNSCCs, where viral expression of the E6 and E7 oncoproteins are necessary for tumor growth and maintenance. Although patients with HPV(+) tumors have a more favorable prognosis, there are currently no HPV-selectiv...

詳細記述

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書誌詳細
出版年:Clin Cancer Res
主要な著者: Brand, Toni M., Hartmann, Stefan, Bhola, Neil E., Peyser, Noah D., Li, Hua, Zeng, Yan, Wechsler, Erin Isaacson, Ranall, Max V., Bandyopadhyay, Sourav, Duvvuri, Umamaheswar, LaVallee, Theresa M., Jordan, Richard C.K., Johnson, Daniel E., Grandis, Jennifer R.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474133/
https://ncbi.nlm.nih.gov/pubmed/27986750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2203
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