Human papillomavirus regulates HER3 expression in head and neck cancer: implications for targeted HER3 therapy in HPV(+) patients

PURPOSE: Human papillomavirus (HPV) 16 plays an etiologic role in a growing subset of HNSCCs, where viral expression of the E6 and E7 oncoproteins are necessary for tumor growth and maintenance. Although patients with HPV(+) tumors have a more favorable prognosis, there are currently no HPV-selectiv...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Brand, Toni M., Hartmann, Stefan, Bhola, Neil E., Peyser, Noah D., Li, Hua, Zeng, Yan, Wechsler, Erin Isaacson, Ranall, Max V., Bandyopadhyay, Sourav, Duvvuri, Umamaheswar, LaVallee, Theresa M., Jordan, Richard C.K., Johnson, Daniel E., Grandis, Jennifer R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474133/
https://ncbi.nlm.nih.gov/pubmed/27986750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2203
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