Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Human papillomavirus (HPV) type 16 is implicated in approximately 75% of head and neck squamous cell carcinomas (HNSCC) that arise in the oropharynx, where viral expression of the E6 and E7 oncoproteins promote cellular transformation, tumor growth, and maintenance. An important oncogenic signaling...

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Bibliografiset tiedot
Julkaisussa:Cancer Res
Päätekijät: Brand, Toni M., Hartmann, Stefan, Bhola, Neil E., Li, Hua, Zeng, Yan, O’Keefe, Rachel A., Ranall, Max V., Bandyopadhyay, Sourav, Soucheray, Margaret, Krogan, Nevan J., Kemp, Carolyn, Duvvuri, Umamaheswar, LaVallee, Theresa, Johnson, Daniel E., Ozbun, Michelle A., Bauman, Julie E., Grandis, Jennifer R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537867/
https://ncbi.nlm.nih.gov/pubmed/29440171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1672
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