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Targeting the IL-6/JAK/STAT3 signalling axis in cancer
The IL-6/JAK/STAT3 pathway is aberrantly hyperactivated in many types of cancer, and such hyperactivation is generally associated with a poor clinical prognosis. In the tumour microenvironment, IL-6/JAK/STAT3 signalling acts to drive the proliferation, survival, invasiveness, and metastasis of tumou...
में बचाया:
| में प्रकाशित: | Nat Rev Clin Oncol |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5858971/ https://ncbi.nlm.nih.gov/pubmed/29405201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2018.8 |
| टैग : |
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