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Biochemical Properties of a Decoy Oligodeoxynucleotide Inhibitor of STAT3 Transcription Factor

Cyclic STAT3 decoy (CS3D) is a second-generation, double-stranded oligodeoxynucleotide (ODN) that mimics a genomic response element for signal transducer and activator of transcription 3 (STAT3), an oncogenic transcription factor. CS3D competitively inhibits STAT3 binding to target gene promoters, r...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lee, David S., O’Keefe, Rachel A., Ha, Patrick K., Grandis, Jennifer R., Johnson, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032396/
https://ncbi.nlm.nih.gov/pubmed/29848966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061608
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