Human papillomavirus regulates HER3 expression in head and neck cancer: implications for targeted HER3 therapy in HPV(+) patients

PURPOSE: Human papillomavirus (HPV) 16 plays an etiologic role in a growing subset of HNSCCs, where viral expression of the E6 and E7 oncoproteins are necessary for tumor growth and maintenance. Although patients with HPV(+) tumors have a more favorable prognosis, there are currently no HPV-selectiv...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: Brand, Toni M., Hartmann, Stefan, Bhola, Neil E., Peyser, Noah D., Li, Hua, Zeng, Yan, Wechsler, Erin Isaacson, Ranall, Max V., Bandyopadhyay, Sourav, Duvvuri, Umamaheswar, LaVallee, Theresa M., Jordan, Richard C.K., Johnson, Daniel E., Grandis, Jennifer R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474133/
https://ncbi.nlm.nih.gov/pubmed/27986750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2203
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