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INCREASED EXPRESSION OF HER2, HER3 and HER2:HER3 HETERODIMERS IN HPV-POSITIVE HNSCC USING A NOVEL PROXIMITY-BASED ASSAY: IMPLICATIONS FOR TARGETED THERAPIES
PURPOSE: In other cancer types, HPV infection has been reported to coincide with overexpression of HER2 and HER3, however the association between HER2 or HER3 expression or dimer formation in HNSCC has not been reported. Overexpression of HER2 and HER3 may contribute to resistance to EGFR inhibitors...
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| Publicado en: | Clin Cancer Res |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609280/ https://ncbi.nlm.nih.gov/pubmed/26138066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3338 |
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