INCREASED EXPRESSION OF HER2, HER3 and HER2:HER3 HETERODIMERS IN HPV-POSITIVE HNSCC USING A NOVEL PROXIMITY-BASED ASSAY: IMPLICATIONS FOR TARGETED THERAPIES

PURPOSE: In other cancer types, HPV infection has been reported to coincide with overexpression of HER2 and HER3, however the association between HER2 or HER3 expression or dimer formation in HNSCC has not been reported. Overexpression of HER2 and HER3 may contribute to resistance to EGFR inhibitors...

Full description

Saved in:
Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Pollock, Netanya I., Wang, Lin, Wallweber, Gerald, Gooding, William E, Huang, Weidong, Chenna, Ahmed, Winslow, John, Sen, Malabika, DeGrave, Kara, Li, Hua, Zeng, Y, Grandis, Jennifer R.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609280/
https://ncbi.nlm.nih.gov/pubmed/26138066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3338
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items