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INCREASED EXPRESSION OF HER2, HER3 and HER2:HER3 HETERODIMERS IN HPV-POSITIVE HNSCC USING A NOVEL PROXIMITY-BASED ASSAY: IMPLICATIONS FOR TARGETED THERAPIES

PURPOSE: In other cancer types, HPV infection has been reported to coincide with overexpression of HER2 and HER3, however the association between HER2 or HER3 expression or dimer formation in HNSCC has not been reported. Overexpression of HER2 and HER3 may contribute to resistance to EGFR inhibitors...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Cancer Res
Prif Awduron: Pollock, Netanya I., Wang, Lin, Wallweber, Gerald, Gooding, William E, Huang, Weidong, Chenna, Ahmed, Winslow, John, Sen, Malabika, DeGrave, Kara, Li, Hua, Zeng, Y, Grandis, Jennifer R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609280/
https://ncbi.nlm.nih.gov/pubmed/26138066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3338
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