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Overexpression-mediated activation of MET in the Golgi promotes HER3/ERBB3 phosphorylation

Ligand-dependent oligomerization of receptor tyrosine kinases (RTKs) results in their activation through highly specific conformational changes in the extracellular and intracellular receptor domains. These conformational changes are unique for each RTK sub-family, limiting cross-activation between...

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Bibliografske podrobnosti
izdano v:Oncogene
Main Authors: Frazier, Nicole Michael, Brand, Toni, Gordan, John D., Grandis, Jennifer, Jura, Natalia
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417953/
https://ncbi.nlm.nih.gov/pubmed/30390071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0537-0
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