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EGF and NRG induce phosphorylation of HER3/ERBB3 by EGFR using distinct oligomeric mechanisms

Heteromeric interactions between the catalytically impaired human epidermal growth factor receptor (HER3/ERBB3) and its catalytically active homologs EGFR and HER2 are essential for their signaling. Different ligands can activate these receptor pairs but lead to divergent signaling outcomes through...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: van Lengerich, Bettina, Agnew, Christopher, Puchner, Elias M., Huang, Bo, Jura, Natalia
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389333/
https://ncbi.nlm.nih.gov/pubmed/28320942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617994114
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