טוען...
Phosphorylated EGFR Dimers Are Not Sufficient to Activate Ras
Growth factor binding to EGFR drives conformational changes that promote homodimerization and transphosphorylation, followed by adaptor recruitment, oligomerization, and signaling through Ras. Whether specific receptor conformations and oligomerization states are necessary for efficient activation o...
שמור ב:
| הוצא לאור ב: | Cell Rep |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5916813/ https://ncbi.nlm.nih.gov/pubmed/29514089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.031 |
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