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Multisite EGFR phosphorylation is regulated by adaptor protein abundances and dimer lifetimes

Differential epidermal growth factor receptor (EGFR) phosphorylation is thought to couple receptor activation to distinct signaling pathways. However, the molecular mechanisms responsible for biased signaling are unresolved due to a lack of insight into the phosphorylation patterns of full-length EG...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Salazar-Cavazos, Emanuel, Nitta, Carolina Franco, Mitra, Eshan D., Wilson, Bridget S., Lidke, Keith A., Hlavacek, William S., Lidke, Diane S.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202077/
https://ncbi.nlm.nih.gov/pubmed/31913761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-09-0548
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