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Multisite EGFR phosphorylation is regulated by adaptor protein abundances and dimer lifetimes

Differential epidermal growth factor receptor (EGFR) phosphorylation is thought to couple receptor activation to distinct signaling pathways. However, the molecular mechanisms responsible for biased signaling are unresolved due to a lack of insight into the phosphorylation patterns of full-length EG...

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Bibliografske podrobnosti
izdano v:Mol Biol Cell
Main Authors: Salazar-Cavazos, Emanuel, Nitta, Carolina Franco, Mitra, Eshan D., Wilson, Bridget S., Lidke, Keith A., Hlavacek, William S., Lidke, Diane S.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202077/
https://ncbi.nlm.nih.gov/pubmed/31913761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-09-0548
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