Recruitment of the Adaptor Protein Grb2 to EGFR Tetramers

[Image: see text] Adaptor protein Grb2 binds phosphotyrosines in the epidermal growth factor (EGF) receptor (EGFR) and thereby links receptor activation to intracellular signaling cascades. Here, we investigated how recruitment of Grb2 to EGFR is affected by the spatial organization and quaternary s...

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Bibliografiske detaljer
Main Authors: Kozer, Noga, Barua, Dipak, Henderson, Christine, Nice, Edouard C., Burgess, Antony W., Hlavacek, William S., Clayton, Andrew H. A.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010257/
https://ncbi.nlm.nih.gov/pubmed/24697349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500182x
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