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Exploring higher-order EGFR oligomerisation and phosphorylation—a combined experimental and theoretical approach()

The epidermal growth factor receptor (EGFR) kinase is generally considered to be activated by either ligand-induced dimerisation or a ligand-induced conformational change within pre-formed dimers. Ligand-induced higher-order EGFR oligomerisation or clustering has been reported but it is not clear ho...

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Detalhes bibliográficos
Main Authors: Kozer, Noga, Barua, Dipak, Orchard, Suzanne, Nice, Eduoard C., Burgess, Antony W., Hlavacek, William S., Clayton, Andrew H.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698845/
https://ncbi.nlm.nih.gov/pubmed/23629589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mb70073a
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