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ERK Nuclear Translocation Is Dimerization-independent but Controlled by the Rate of Phosphorylation
Upon activation, ERKs translocate from the cytoplasm to the nucleus. This process is required for the induction of many cellular responses, yet the molecular mechanisms that regulate ERK nuclear translocation are not fully understood. We have used a mouse embryo fibroblast ERK1-knock-out cell line e...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823437/ https://ncbi.nlm.nih.gov/pubmed/19920141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.064972 |
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