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Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme
Crystal structures of enzymes are indispensable to understanding their mechanisms on a molecular level. It, however, remains challenging to determine which structures are adopted in solution, especially for dynamic complexes. Here, we study the bilobed decapping enzyme Dcp2 that removes the 5′ cap s...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5468633/ https://ncbi.nlm.nih.gov/pubmed/28533364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704496114 |
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