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Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme

The 5′ messenger RNA (mRNA) cap structure enhances translation and protects the transcript against exonucleolytic degradation. During mRNA turnover, this cap is removed from the mRNA. This decapping step is catalyzed by the Scavenger Decapping Enzyme (DcpS), in case the mRNA has been exonucleolyticl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Fuchs, Anna-Lisa, Wurm, Jan Philip, Neu, Ancilla, Sprangers, Remco
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431086/
https://ncbi.nlm.nih.gov/pubmed/32723815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009362117
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