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Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme

The 5′ messenger RNA (mRNA) cap structure enhances translation and protects the transcript against exonucleolytic degradation. During mRNA turnover, this cap is removed from the mRNA. This decapping step is catalyzed by the Scavenger Decapping Enzyme (DcpS), in case the mRNA has been exonucleolyticl...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Fuchs, Anna-Lisa, Wurm, Jan Philip, Neu, Ancilla, Sprangers, Remco
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431086/
https://ncbi.nlm.nih.gov/pubmed/32723815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009362117
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