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Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS

Eukaryotic 5′ mRNA cap structures participate to the post-transcriptional control of gene expression before being released by the two main mRNA decay pathways. In the 3′-5′ pathway, the exosome generates free cap dinucleotides (m7GpppN) or capped oligoribonucleotides that are hydrolyzed by the Scave...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Taverniti, Valerio, Séraphin, Bertrand
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
RNA
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288156/
https://ncbi.nlm.nih.gov/pubmed/25432955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1251
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