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The human decapping scavenger enzyme DcpS modulates microRNA turnover

The decapping scavenger enzyme DcpS is known for its role in hydrolyzing the cap structure following mRNA degradation. Recently, we discovered a new function in miRNA degradation activation for the ortholog of DcpS in C. elegans. Here we show that human DcpS conserves its role in miRNA turnover. In...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Meziane, Oussama, Piquet, Sandra, Bossé, Gabriel D., Gagné, Dominic, Paquet, Eric, Robert, Claude, Tones, Michael A., Simard, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653633/
https://ncbi.nlm.nih.gov/pubmed/26584588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16688
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