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Mechanistic and Kinetic Analysis of the DcpS Scavenger Decapping Enzyme

Decapping is an important process in the control of eukaryotic mRNA degradation. The scavenger decapping enzyme DcpS functions to clear the cell of cap structure following decay of the RNA body by catalyzing the hydrolysis of m(7)GpppN to m(7)Gp and ppN. Structural analysis has revealed that DcpS is...

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Bibliographic Details
Main Authors: Liu, Shin-Wu, Rajagopal, Vaishnavi, Patel, Smita S., Kiledjian, Megerditch
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423256/
https://ncbi.nlm.nih.gov/pubmed/18441014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800341200
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