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Mechanistic and Kinetic Analysis of the DcpS Scavenger Decapping Enzyme

Decapping is an important process in the control of eukaryotic mRNA degradation. The scavenger decapping enzyme DcpS functions to clear the cell of cap structure following decay of the RNA body by catalyzing the hydrolysis of m(7)GpppN to m(7)Gp and ppN. Structural analysis has revealed that DcpS is...

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Autori principali: Liu, Shin-Wu, Rajagopal, Vaishnavi, Patel, Smita S., Kiledjian, Megerditch
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423256/
https://ncbi.nlm.nih.gov/pubmed/18441014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800341200
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