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Dcp2: an mRNA decapping enzyme that adopts many different shapes and forms

Eukaryotic mRNAs contain a 5’ cap structure that protects the transcript against rapid exonucleolytic degradation. The regulation of cellular mRNA levels therefore depends on a precise control of the mRNA decapping pathways. The major mRNA decapping enzyme in eukaryotic cells is Dcp2. It is regulate...

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Détails bibliographiques
Publié dans:Curr Opin Struct Biol
Auteurs principaux: Wurm, Jan Philip, Sprangers, Remco
Format: Artigo
Langue:Inglês
Publié: Elsevier Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900585/
https://ncbi.nlm.nih.gov/pubmed/31473440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.07.009
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