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Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme.

A major mechanism of mRNA decay occurs by the process of deadenylation, decapping and 5' --> 3' exonucleolytic degradation. Recently, the product of the DCP1 gene has been shown to be required for decapping mRNAs in vivo and co-purifies with decapping activity in vitro. We have purified...

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Detalhes bibliográficos
Main Authors: LaGrandeur, T E, Parker, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170496/
https://ncbi.nlm.nih.gov/pubmed/9482745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.5.1487
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