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Functional characterization of the mammalian mRNA decapping enzyme hDcp2

Regulation of decapping is a critical determinant of mRNA stability. We recently identified hDcp2 as a human decapping enzyme with intrinsic decapping activity. This activity is specific to N(7)-methylated guanosine containing RNA. The hDcp2 enzyme does not function on the cap structure alone and is...

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Detalhes bibliográficos
Main Authors: PICCIRILLO, CHRISTOPHER, KHANNA, RICHIE, KILEDJIAN, MEGERDITCH
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2003 by RNA Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370477/
https://ncbi.nlm.nih.gov/pubmed/12923261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5690503
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