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Poly(A)-binding-protein-mediated regulation of hDcp2 decapping in vitro

Regulation of mRNA decapping is a critical determinant for gene expression. We demonstrate that the poly(A) tail-mediated regulation of mRNA decapping observed in humans can be recapitulated in vitro by the cytoplasmic poly(A)-binding protein PABP through a direct and specific binding to the 5′ end...

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Detalhes bibliográficos
Main Authors: Khanna, Richie, Kiledjian, Megerditch
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC404327/
https://ncbi.nlm.nih.gov/pubmed/15085179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600213
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