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Identification of an erythroid-enriched endoribonuclease activity involved in specific mRNA cleavage

Stability of the human α–globin mRNA is conferred by a ribonucleoprotein complex termed the α–complex, which acts by impeding deadenylation. Using our recently devised in vitro decay assay, we demonstrate that the α–complex also functions by protecting the 3′–untranslated region (3′-UTR) from an ery...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Wang, Zuoren, Kiledjian, Megerditch
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2000
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305563/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10637233/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.2.295
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