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Identification of an erythroid-enriched endoribonuclease activity involved in specific mRNA cleavage

Stability of the human α–globin mRNA is conferred by a ribonucleoprotein complex termed the α–complex, which acts by impeding deadenylation. Using our recently devised in vitro decay assay, we demonstrate that the α–complex also functions by protecting the 3′–untranslated region (3′-UTR) from an ery...

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Hlavní autoři: Wang, Zuoren, Kiledjian, Megerditch
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC305563/
https://ncbi.nlm.nih.gov/pubmed/10637233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.2.295
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