Identification of an erythroid-enriched endoribonuclease activity involved in specific mRNA cleavage
Stability of the human α–globin mRNA is conferred by a ribonucleoprotein complex termed the α–complex, which acts by impeding deadenylation. Using our recently devised in vitro decay assay, we demonstrate that the α–complex also functions by protecting the 3′–untranslated region (3′-UTR) from an ery...
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| Publié dans: | EMBO J |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305563/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10637233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.2.295 |
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