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The hDcp2 protein is a mammalian mRNA decapping enzyme
Decapping of mRNA is a critical step in eukaryotic mRNA turnover, yet the proteins involved in this activity remain elusive in mammals. We identified the human Dcp2 protein (hDcp2) as an enzyme containing intrinsic decapping activity. hDcp2 specifically hydrolyzed methylated capped RNA to release m(...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC130517/ https://ncbi.nlm.nih.gov/pubmed/12218187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192445599 |
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