Poly(A)-binding-protein-mediated regulation of hDcp2 decapping in vitro

Regulation of mRNA decapping is a critical determinant for gene expression. We demonstrate that the poly(A) tail-mediated regulation of mRNA decapping observed in humans can be recapitulated in vitro by the cytoplasmic poly(A)-binding protein PABP through a direct and specific binding to the 5′ end...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Khanna, Richie, Kiledjian, Megerditch
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2004
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC404327/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15085179/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600213
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