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The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface
The removal of the 5′ 7-methylguanosine mRNA cap structure (decapping) is a central step in the 5′–3′ mRNA degradation pathway and is performed by the Dcp1:Dcp2 decapping complex. The activity of this complex is tightly regulated to prevent premature degradation of the transcript. Here, we establish...
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Vydáno v: | RNA |
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Hlavní autoři: | , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Cold Spring Harbor Laboratory Press
2016
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4986892/ https://ncbi.nlm.nih.gov/pubmed/27354705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.057315.116 |
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