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Fidelity of Nucleotide Incorporation by the RNA-Dependent RNA Polymerase from Poliovirus
Using poliovirus (PV) and its RNA-dependent RNA polymerase (RdRp) as our primary model system, we have advanced knowledge fundamental to the chemistry and fidelity of nucleotide addition by nucleic acid polymerase. Two fidelity checkpoints exist prior to nucleotide addition. The first toggles the en...
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| Published in: | Enzymes |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458529/ https://ncbi.nlm.nih.gov/pubmed/27241934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.enz.2016.02.002 |
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