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Incorporation fidelity of the viral RNA-dependent RNA polymerase: a kinetic, thermodynamic and structural perspective()

Positive-strand RNA viruses exist as a quasi-species due to the incorporation of mutations into the viral genome during replication by the virus-encoded RNA-dependent RNA polymerase (RdRP). Therefore, the RdRP is often described as a low-fidelity enzyme. However, until recently, a complete descripti...

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Detalhes bibliográficos
Publicado no:Virus Res
Main Authors: Castro, Christian, Arnold, Jamie J., Cameron, Craig E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125856/
https://ncbi.nlm.nih.gov/pubmed/15649560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2004.11.004
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